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Vectors for Human GBA1

Gene Information

  • Offical Gene Symbol GBA1
  • Species Human (Homo sapiens)
  • Offical Full Name glucosylceramidase beta 1
  • Other Aliases GBA; GCB; GLUC
  • Other Desigations lysosomal acid glucosylceramidase; D-glucosyl-N-acylsphingosine glucohydrolase; SGTase; acid beta-glucosidase; alglucerase; beta-GC; beta-glucocerebrosidase; beta-glucosylceramidase 1; cholesterol glucosyltransferase; cholesteryl-beta-glucosidase; glucocerebrosidase; glucosidase, beta, acid; glucosylceramidase-like protein; imiglucerase; lysosomal acid GCase; lysosomal cholesterol glycosyltransferase; lysosomal galactosylceramidase; lysosomal glucocerebrosidase; lysosomal glycosylceramidase
  • Gene Type protein-coding
  • Summary
    This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
  • NCBI Gene ID 2629
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human GBA1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GBA1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human GBA1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human GBA1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human GBA1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human GBA1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GBA1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human GBA1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human GBA1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human GBA1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GBA1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human GBA1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human GBA1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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