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Vectors for Human HIRA

Gene Information

  • Offical Gene Symbol HIRA
  • Species Human (Homo sapiens)
  • Offical Full Name histone cell cycle regulator
  • Other Aliases DGCR1; TUP1; TUPLE1
  • Other Desigations protein HIRA; DiGeorge critical region gene 1; HIR histone cell cycle regulation defective homolog A; TUP1-like enhancer of split protein 1; histone regulator A
  • Gene Type protein-coding
  • Summary
    This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 7290
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human HIRA(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HIRA expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human HIRA expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human HIRA expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human HIRA expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human HIRA expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HIRA shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human HIRA shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human HIRA shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human HIRA shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HIRA CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
View Vector 
Human HIRA CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human HIRA CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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