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Vectors for Human IRGM

Gene Information

  • Offical Gene Symbol IRGM
  • Species Human (Homo sapiens)
  • Offical Full Name immunity related GTPase M
  • Other Aliases IBD19; IFI1; IRGM1; LRG-47; LRG47
  • Other Desigations immunity-related GTPase family M protein; LPS-stimulated RAW 264.7 macrophage protein 47 homolog; LRG-47-like protein; immunity-related GTPase family, M1; interferon-inducible protein 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn\'s disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
  • NCBI Gene ID 345611
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human IRGM(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human IRGM expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human IRGM expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human IRGM expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human IRGM expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human IRGM expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human IRGM shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human IRGM shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
View Vector 
Human IRGM shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human IRGM shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human IRGM CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human IRGM CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human IRGM CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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