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Vectors for Human ITGB3BP

Gene Information

  • Offical Gene Symbol ITGB3BP
  • Species Human (Homo sapiens)
  • Offical Full Name integrin subunit beta 3 binding protein
  • Other Aliases CENP-R; CENPR; HSU37139; NRIF3; TAP20
  • Other Desigations centromere protein R; beta 3 endonexin; beta3-endonexin; integrin beta 3 binding protein (beta3-endonexin); integrin beta-3-binding protein; nuclear receptor-interacting factor 3
  • Gene Type protein-coding
  • Summary
    This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
  • NCBI Gene ID 23421
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human ITGB3BP(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ITGB3BP expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human ITGB3BP expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human ITGB3BP expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human ITGB3BP expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human ITGB3BP expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ITGB3BP shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human ITGB3BP shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human ITGB3BP shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human ITGB3BP shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ITGB3BP CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human ITGB3BP CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human ITGB3BP CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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