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Vectors for Human KLK6

Gene Information

  • Offical Gene Symbol KLK6
  • Species Human (Homo sapiens)
  • Offical Full Name kallikrein related peptidase 6
  • Other Aliases Bssp; Klk7; PRSS18; PRSS9; SP59; hK6
  • Other Desigations kallikrein-6; neurosin; protease M; serine protease 18; serine protease 9; zyme
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer\'s and Parkinson\'s disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
  • NCBI Gene ID 5653
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human KLK6(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human KLK6 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human KLK6 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human KLK6 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human KLK6 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human KLK6 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human KLK6 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human KLK6 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human KLK6 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human KLK6 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human KLK6 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human KLK6 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human KLK6 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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