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Vectors for Human LGI1

Gene Information

  • Offical Gene Symbol LGI1
  • Species Human (Homo sapiens)
  • Offical Full Name leucine rich glioma inactivated 1
  • Other Aliases ADLTE; ADPAEF; ADPEAF; EPITEMPIN; EPT; ETL1; IB1099
  • Other Desigations leucine-rich glioma-inactivated protein 1; epitempin-1
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
  • NCBI Gene ID 9211
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human LGI1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LGI1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human LGI1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human LGI1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human LGI1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human LGI1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LGI1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human LGI1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human LGI1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human LGI1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LGI1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human LGI1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human LGI1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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