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Vectors for Human MACC1

Gene Information

  • Offical Gene Symbol MACC1
  • Species Human (Homo sapiens)
  • Offical Full Name MET transcriptional regulator MACC1
  • Other Aliases 7A5; SH3BP4L
  • Other Desigations metastasis-associated in colon cancer protein 1; MACC1, MET transcriptional regulator; SH3 domain-containing protein 7a5; metastasis associated in colon cancer 1; putative binding protein 7a5
  • Gene Type protein-coding
  • Summary
    MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009]
  • NCBI Gene ID 346389
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human MACC1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MACC1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human MACC1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human MACC1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human MACC1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human MACC1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MACC1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human MACC1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human MACC1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human MACC1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MACC1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human MACC1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human MACC1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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