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Vectors for Human MAP4K2

Gene Information

  • Offical Gene Symbol MAP4K2
  • Species Human (Homo sapiens)
  • Offical Full Name mitogen-activated protein kinase kinase kinase kinase 2
  • Other Aliases BL44; GCK; RAB8IP
  • Other Desigations mitogen-activated protein kinase kinase kinase kinase 2; B lymphocyte serine/threonine protein kinase; MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; Rab8 interacting protein; germinal centre kinase (GC kinase)
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
  • NCBI Gene ID 5871
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human MAP4K2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MAP4K2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human MAP4K2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human MAP4K2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human MAP4K2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human MAP4K2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MAP4K2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human MAP4K2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human MAP4K2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human MAP4K2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MAP4K2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human MAP4K2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human MAP4K2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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