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Vectors for Human MED27

Gene Information

  • Offical Gene Symbol MED27
  • Species Human (Homo sapiens)
  • Offical Full Name mediator complex subunit 27
  • Other Aliases CRAP34; CRSP34; CRSP8; MED3; NEDSCAC; TRAP37
  • Other Desigations mediator of RNA polymerase II transcription subunit 27; CRSP complex subunit 8; cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa; epididymis secretory sperm binding protein; p37 TRAP/SMCC/PC2 subunit; transcriptional coactivator CRSP34
  • Gene Type protein-coding
  • Summary
    The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
  • NCBI Gene ID 9442
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human MED27(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MED27 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human MED27 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human MED27 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human MED27 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human MED27 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MED27 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human MED27 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human MED27 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human MED27 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MED27 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human MED27 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human MED27 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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