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Vectors for Human NLRP11

Gene Information

  • Offical Gene Symbol NLRP11
  • Species Human (Homo sapiens)
  • Offical Full Name NLR family pyrin domain containing 11
  • Other Aliases CLR19.6; NALP11; NOD17; PAN10; PYPAF6; PYPAF7
  • Other Desigations NACHT, LRR and PYD domains-containing protein 11; NACHT, leucine rich repeat and PYD containing 11; PAAD- and NACHT-containing protein 10B; PAAD-and NACHT domain-containing protein 10; PYRIN-containing APAF1-like protein 6; nucleotide-binding oligomerization domain protein 17; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11
  • Gene Type protein-coding
  • Summary
    This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms. [provided by RefSeq, May 2017]
  • NCBI Gene ID 204801
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human NLRP11(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NLRP11 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human NLRP11 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human NLRP11 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human NLRP11 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human NLRP11 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NLRP11 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human NLRP11 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human NLRP11 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human NLRP11 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NLRP11 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human NLRP11 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human NLRP11 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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