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Vectors for Human NLRP12

Gene Information

  • Offical Gene Symbol NLRP12
  • Species Human (Homo sapiens)
  • Offical Full Name NLR family pyrin domain containing 12
  • Other Aliases CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2
  • Other Desigations NACHT, LRR and PYD domains-containing protein 12; PYRIN-containing APAF1-like protein 7; monarch 1; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12; regulated by nitric oxide
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
  • NCBI Gene ID 91662
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human NLRP12(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NLRP12 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human NLRP12 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human NLRP12 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human NLRP12 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human NLRP12 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NLRP12 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human NLRP12 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human NLRP12 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human NLRP12 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NLRP12 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human NLRP12 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human NLRP12 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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