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Vectors for Human NTAN1

Gene Information

  • Offical Gene Symbol NTAN1
  • Species Human (Homo sapiens)
  • Offical Full Name N-terminal asparagine amidase
  • Other Aliases PNAA; PNAD
  • Other Desigations protein N-terminal asparagine amidohydrolase; protein N-terminal Asn amidase; protein N-terminal asparagine amidase; protein NH2-terminal asparagine deamidase; protein NTN-amidase
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
  • NCBI Gene ID 123803
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human NTAN1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NTAN1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human NTAN1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human NTAN1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human NTAN1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human NTAN1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NTAN1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human NTAN1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human NTAN1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human NTAN1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NTAN1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human NTAN1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human NTAN1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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