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Vectors for Human PATZ1

Gene Information

  • Offical Gene Symbol PATZ1
  • Species Human (Homo sapiens)
  • Offical Full Name POZ/BTB and AT hook containing zinc finger 1
  • Other Aliases MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG; dJ400N23
  • Other Desigations POZ-, AT hook-, and zinc finger-containing protein 1; BTB-POZ domain zinc finger transcription factor; MAZ-related factor; POZ-AT hook-zinc finger protein; protein kinase A RI subunit alpha-associated protein; zinc finger and BTB domain-containing protein 19; zinc finger protein 278; zinc finger sarcoma gene protein
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 23598
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human PATZ1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PATZ1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human PATZ1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human PATZ1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human PATZ1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human PATZ1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PATZ1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human PATZ1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human PATZ1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human PATZ1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PATZ1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human PATZ1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human PATZ1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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