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Vectors for Human PDE6A

Gene Information

  • Offical Gene Symbol PDE6A
  • Species Human (Homo sapiens)
  • Offical Full Name phosphodiesterase 6A
  • Other Aliases CGPR-A; PDEA; RP43
  • Other Desigations rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; GMP-PDE alpha; PDE V-B1; cGMP phosphodiesterase alpha subunit; phosphodiesterase 6A, cGMP-specific, rod, alpha; retinitis pigmentosa type 43; rod photoreceptor cGMP phosphodiesterase alpha subunit
  • Gene Type protein-coding
  • Summary
    This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 5145
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human PDE6A(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PDE6A expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human PDE6A expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human PDE6A expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human PDE6A expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human PDE6A expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PDE6A shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human PDE6A shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human PDE6A shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human PDE6A shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PDE6A CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human PDE6A CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human PDE6A CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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