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Vectors for Human PDHB

Gene Information

  • Offical Gene Symbol PDHB
  • Species Human (Homo sapiens)
  • Offical Full Name pyruvate dehydrogenase E1 subunit beta
  • Other Aliases E1beta; PDHBD; PDHE1-B; PDHE1B; PHE1B
  • Other Desigations pyruvate dehydrogenase E1 component subunit beta, mitochondrial; epididymis secretory sperm binding protein; pyruvate dehydrogenase (lipoamide) beta; pyruvate dehydrogenase E1 beta subunit; pyruvate dehydrogenase, E1 beta polypeptide
  • Gene Type protein-coding
  • Summary
    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
  • NCBI Gene ID 5162
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human PDHB(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PDHB expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human PDHB expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human PDHB expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human PDHB expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human PDHB expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PDHB shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human PDHB shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human PDHB shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human PDHB shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PDHB CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human PDHB CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human PDHB CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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