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Vectors for Human PLEKHG4

Gene Information

  • Offical Gene Symbol PLEKHG4
  • Species Human (Homo sapiens)
  • Offical Full Name pleckstrin homology and RhoGEF domain containing G4
  • Other Aliases ARHGEF44; PRTPHN1; SCA4
  • Other Desigations puratrophin-1; PH domain-containing family G member 4; Purkinje cell atrophy associated protein 1; pleckstrin homology domain containing, family G (with RhoGef domain) member 4
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  • NCBI Gene ID 25894
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PLEKHG4(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PLEKHG4 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PLEKHG4 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PLEKHG4 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PLEKHG4 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PLEKHG4 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PLEKHG4 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human PLEKHG4 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human PLEKHG4 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human PLEKHG4 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PLEKHG4 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human PLEKHG4 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PLEKHG4 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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