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Vectors for Human PTPN13

Gene Information

  • Offical Gene Symbol PTPN13
  • Species Human (Homo sapiens)
  • Offical Full Name protein tyrosine phosphatase non-receptor type 13
  • Other Aliases FAP-1; PNP1; PTP-BAS; PTP-BL; PTP1E; PTPL1; PTPLE; hPTP1E
  • Other Desigations tyrosine-protein phosphatase non-receptor type 13; fas-associated protein-tyrosine phosphatase 1; hPTPE1; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase); protein-tyrosine phosphatase 1E; protein-tyrosine phosphatase PTPL1
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008]
  • NCBI Gene ID 5783
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PTPN13(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTPN13 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PTPN13 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PTPN13 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PTPN13 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PTPN13 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTPN13 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human PTPN13 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human PTPN13 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human PTPN13 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTPN13 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human PTPN13 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PTPN13 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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