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Vectors for Human PTPN18

Gene Information

  • Offical Gene Symbol PTPN18
  • Species Human (Homo sapiens)
  • Offical Full Name protein tyrosine phosphatase non-receptor type 18
  • Other Aliases BDP1; PTP-HSCF
  • Other Desigations tyrosine-protein phosphatase non-receptor type 18; brain-derived phosphatase; protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
  • NCBI Gene ID 26469
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PTPN18(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTPN18 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PTPN18 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PTPN18 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PTPN18 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PTPN18 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTPN18 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human PTPN18 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human PTPN18 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human PTPN18 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTPN18 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human PTPN18 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PTPN18 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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