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Vectors for Human RAPGEF5

Gene Information

  • Offical Gene Symbol RAPGEF5
  • Species Human (Homo sapiens)
  • Offical Full Name Rap guanine nucleotide exchange factor 5
  • Other Aliases GFR; MR-GEF; MRGEF; REPAC
  • Other Desigations rap guanine nucleotide exchange factor 5; M-Ras-regulated GEF; M-Ras-regulated Rap GEF; Rap guanine nucleotide exchange factor (GEF) 5; guanine nucleotide exchange factor for Rap1; related to Epac
  • Gene Type protein-coding
  • Summary
    Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
  • NCBI Gene ID 9771
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human RAPGEF5(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RAPGEF5 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human RAPGEF5 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human RAPGEF5 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human RAPGEF5 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human RAPGEF5 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RAPGEF5 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human RAPGEF5 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human RAPGEF5 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human RAPGEF5 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RAPGEF5 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human RAPGEF5 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human RAPGEF5 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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