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Vectors for Human RNF8

Gene Information

  • Offical Gene Symbol RNF8
  • Species Human (Homo sapiens)
  • Offical Full Name ring finger protein 8
  • Other Aliases hRNF8
  • Other Desigations E3 ubiquitin-protein ligase RNF8; C3HC4-type zinc finger protein; RING-type E3 ubiquitin transferase RNF8; UBC13/UEV-interacting ring finger protein; ring finger protein (C3HC4 type) 8; ring finger protein 8, E3 ubiquitin protein ligase
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
  • NCBI Gene ID 9025
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human RNF8(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RNF8 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human RNF8 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human RNF8 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human RNF8 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human RNF8 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RNF8 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human RNF8 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human RNF8 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human RNF8 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RNF8 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human RNF8 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human RNF8 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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