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Vectors for Human RUNX1

Gene Information

  • Offical Gene Symbol RUNX1
  • Species Human (Homo sapiens)
  • Offical Full Name RUNX family transcription factor 1
  • Other Aliases AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2aB; PEBP2alpha
  • Other Desigations runt-related transcription factor 1; AML1-ETO fusion; AML1-ETO fusion protein; AML1-EVI-1 fusion protein; PEA2-alpha B; PEBP2-alpha B; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor alpha B subunit; acute myeloid leukemia 1 protein; core-binding factor, runt domain, alpha subunit 2; mutant RUNX1; oncogene AML-1; polyomavirus enhancer-binding protein 2 alpha B subunit; runt related transcription factor 1
  • Gene Type protein-coding
  • Summary
    Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 861
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human RUNX1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RUNX1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human RUNX1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human RUNX1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human RUNX1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human RUNX1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RUNX1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human RUNX1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human RUNX1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human RUNX1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RUNX1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human RUNX1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human RUNX1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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