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Vectors for Human SCN8A

Gene Information

  • Offical Gene Symbol SCN8A
  • Species Human (Homo sapiens)
  • Offical Full Name sodium voltage-gated channel alpha subunit 8
  • Other Aliases BFIS5; CERIII; CIAT; DEE13; EIEE13; MED; MYOCL2; NaCh6; Nav1.6; PN4
  • Other Desigations sodium channel protein type 8 subunit alpha; hNa6/Scn8a voltage-gated sodium channel; sodium channel, voltage gated, type VIII, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.6; voltage-gated sodium channel type VIII alpha protein
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with cognitive disability, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • NCBI Gene ID 6334
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SCN8A(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SCN8A expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human SCN8A expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human SCN8A expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human SCN8A expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human SCN8A expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SCN8A shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human SCN8A shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human SCN8A shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human SCN8A shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SCN8A CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human SCN8A CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human SCN8A CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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