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Vectors for Human SKAP2

Gene Information

  • Offical Gene Symbol SKAP2
  • Species Human (Homo sapiens)
  • Offical Full Name src kinase associated phosphoprotein 2
  • Other Aliases PRAP; RA70; SAPS; SCAP2; SKAP-HOM; SKAP55R
  • Other Desigations src kinase-associated phosphoprotein 2; Fyn-associated phosphoprotein SKAP55 homologue; Pyk2/RAFTK-associated protein; SKAP-55HOM; SKAP55 homolog; retinoic acid-induced protein 70; src family-associated phosphoprotein 2; src kinase-associated phosphoprotein of 55-related protein; src-associated adapter protein with PH and SH3 domains
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
  • NCBI Gene ID 8935
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SKAP2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SKAP2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human SKAP2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human SKAP2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human SKAP2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human SKAP2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SKAP2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human SKAP2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human SKAP2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human SKAP2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SKAP2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human SKAP2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human SKAP2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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