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Vectors for Human SLC10A2

Gene Information

  • Offical Gene Symbol SLC10A2
  • Species Human (Homo sapiens)
  • Offical Full Name solute carrier family 10 member 2
  • Other Aliases ASBT; IBAT; ISBT; NTCP2; PBAM; PBAM1
  • Other Desigations ileal sodium/bile acid cotransporter; Na(+)-dependent ileal bile acid transporter; Na+/taurocholate cotransporting polypeptide 2; ileal apical sodium-dependent bile acid transporter; ileal bile acid transporter; ileal sodium-dependent bile acid transporter; sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family), member 2; solute carrier family 10 (sodium/bile acid cotransporter), member 2
  • Gene Type protein-coding
  • Summary
    This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]
  • NCBI Gene ID 6555
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SLC10A2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SLC10A2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human SLC10A2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human SLC10A2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human SLC10A2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human SLC10A2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SLC10A2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human SLC10A2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human SLC10A2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human SLC10A2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SLC10A2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human SLC10A2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human SLC10A2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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