Human SLC46A1 (Gene ID: 113235) vectors - Lentivirus, AAV, shRNA & CRISPR I VectorBuilder

Gene Information

Offical Gene Symbol SLC46A1
Species Human (Homo sapiens)
Offical Full Name solute carrier family 46 member 1
Other Aliases G21; HCP1; HsPCFT; PCFT; hPCFT
Other Desigations proton-coupled folate transporter; heme carrier protein 1; solute carrier family 46 (folate transporter), member 1
Gene Type protein-coding
Summary
This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]
NCBI Gene ID 113235
RefSeq Transcript
NM_001242366.3; NM_080669.6
RefSeq Protein
NP_001229295.1; NP_542400.2
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human SLC46A1 expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human SLC46A1 expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human SLC46A1 expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human SLC46A1 expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human SLC46A1 expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human SLC46A1 shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human SLC46A1 shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human SLC46A1 shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human SLC46A1 shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human SLC46A1 CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human SLC46A1 CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human SLC46A1 CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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