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Vectors for Human SLC5A7

Gene Information

  • Offical Gene Symbol SLC5A7
  • Species Human (Homo sapiens)
  • Offical Full Name solute carrier family 5 member 7
  • Other Aliases CHT; CHT1; CMS20; DHMNVP; HMN7A; HMND7; hCHT1
  • Other Desigations high affinity choline transporter 1; Motor neuronopathy, distal hereditary, type VIIA; Motor neuronopathy, distal hereditary, with vocal cord paresis; high affinity choline transporter; hemicholinium-3-sensitive choline transporter; solute carrier family 5 (sodium/choline cotransporter), member 7
  • Gene Type protein-coding
  • Summary
    This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
  • NCBI Gene ID 60482
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human SLC5A7(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SLC5A7 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human SLC5A7 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human SLC5A7 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human SLC5A7 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human SLC5A7 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SLC5A7 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
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Human SLC5A7 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
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Human SLC5A7 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
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Human SLC5A7 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SLC5A7 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human SLC5A7 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human SLC5A7 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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