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Vectors for Human UPF2

Gene Information

  • Offical Gene Symbol UPF2
  • Species Human (Homo sapiens)
  • Offical Full Name UPF2 regulator of nonsense mediated mRNA decay
  • Other Aliases HUPF2; RENT2; smg-3
  • Other Desigations regulator of nonsense transcripts 2; FRS2/UPF2/LEMD3 fusion; LEMD3/UPF2 fusion; UPF2 regulator of nonsense transcripts homolog; nonsense mRNA reducing factor 2; smg-3 homolog, nonsense mediated mRNA decay factor; up-frameshift suppressor 2 homolog; yeast Upf2p homolog
  • Gene Type protein-coding
  • Summary
    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 26019
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human UPF2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UPF2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human UPF2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human UPF2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human UPF2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human UPF2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UPF2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human UPF2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human UPF2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human UPF2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UPF2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human UPF2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human UPF2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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