Click to refer colleagues and get 30% off
  1. Home
  2. Find Popular Vectors
  3. Vectors for Human UPF3B

Vectors for Human UPF3B

Gene Information

  • Offical Gene Symbol UPF3B
  • Species Human (Homo sapiens)
  • Offical Full Name UPF3B regulator of nonsense mediated mRNA decay
  • Other Aliases HUPF3B; MRX62; MRX82; MRXS14; RENT3B; UPF3BP1; UPF3BP2; UPF3BP3; UPF3X; Upf3p-X
  • Other Desigations regulator of nonsense transcripts 3B; UPF3 regulator of nonsense transcripts homolog B; UPF3B pseudogene 1; UPF3B pseudogene 2; UPF3B pseudogene 3; nonfunctional UPF3B regulator of nonsense mediated mRNA decay; nonsense mRNA reducing factor 3B; up-frameshift suppressor 3 homolog B; up-frameshift suppressor 3 homolog on chromosome X
  • Gene Type protein-coding
  • Summary
    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 65109
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human UPF3B(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UPF3B expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human UPF3B expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human UPF3B expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human UPF3B expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human UPF3B expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UPF3B shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human UPF3B shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human UPF3B shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human UPF3B shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UPF3B CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human UPF3B CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human UPF3B CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

Can’t find desired vectors above? Use options below to obtain custom vectors.

Design My Vector

Use this option to design your vector using our online platform.

You can request cloning & virus packaging services for your vector here.

Request Design Support

Use this option to ask our scientists to design your vector for free.

You can also submit other service inquires here, including:

  • Virus packaging
  • CRISPR targeting
  • BAC modification
  • Library construction
  • Plasmid DNA Preparation
  • RNA preparation
  • Mutagenesis
  • and more...