Vectors for Human ZRS

Gene Information

  • Offical Gene Symbol ZRS
  • Species Human (Homo sapiens)
  • Offical Full Name -
  • Other Aliases MFCS1; ZRS/LMBR1; pZRS
  • Other Desigations VISTA enhancer hs2496; ZPA-specific enhancer; ZRS limb enhancer; ZRS/SHH enhancer; mammal-fish-conserved-sequence 1; zone of polarizing activity regulatory sequence
  • Gene Type biological-region
  • Summary
    This locus represents a highly conserved functional element that is located in an intron of the limb development membrane protein 1 (LMBR1) gene. In the developing limb bud, this element functions as a long-range enhancer of the sonic hedgehog signaling molecule (SHH) gene, which is located approximately 1 Mb downstream. Mutations in this element disrupt limb patterning and can result in a range of congenital limb malformations, including preaxial polydactyly, triphalangeal thumbs, Werner mesomelic syndrome (WMS), polysyndactyly, or Laurin-Sandrow syndrome. [provided by RefSeq, Feb 2019]
  • NCBI Gene ID 105804841
  • External Links NCBI UCSC Genome Browser View
No vectors are found in our database for this gene. We may introduce vectors for this gene in the future.

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