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Vectors for Mouse Casr

Gene Information

  • Offical Gene Symbol Casr
  • Species Mouse (Mus musculus)
  • Offical Full Name calcium-sensing receptor
  • Other Aliases CaR; Gprc2a
  • Other Desigations extracellular calcium-sensing receptor; G protein-coupled receptor, family C, group 2, member A; PCaR1; cation sensing receptor; parathyroid cell calcium-sensing receptor
  • Gene Type protein-coding
  • Summary
    Predicted to enable several functions, including integrin binding activity; protein homodimerization activity; and transmembrane transporter binding activity. Acts upstream of or within positive regulation of ATPase activity; positive regulation of gene expression; and regulation of calcium ion transport. Predicted to be located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and neuronal cell body. Predicted to be integral component of plasma membrane. Is expressed in several structures, including branchial pouch; central nervous system; lung; metanephros; and superior cervical ganglion. Used to study autosomal dominant hypocalcemia 1; familial hypocalciuric hypercalcemia 1; and hyperparathyroidism. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant hypocalcemia (multiple); hypercalcemia (multiple); hyperparathyroidism (multiple); idiopathic generalized epilepsy 8; and nephrolithiasis (multiple). Orthologous to human CASR (calcium sensing receptor). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 12374
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Casr(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Casr expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Casr expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Casr expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Casr expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Casr expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Casr shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Casr shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Casr shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Casr shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Casr CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Casr CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Casr CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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