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Vectors for Mouse Kdm2b

Gene Information

  • Offical Gene Symbol Kdm2b
  • Species Mouse (Mus musculus)
  • Offical Full Name lysine (K)-specific demethylase 2B
  • Other Aliases Cxxc2; Fbl10; Fbxl10; Jhdm1b; PCCX2
  • Other Desigations lysine-specific demethylase 2B; F-box and leucine-rich repeat protein 10; F-box protein FBL10; F-box protein containing leucine repeats 10; F-box/LRR-repeat protein 10; [Histone-H3]-lysine-36 demethylase 1B; jmjC domain-containing histone demethylation protein 1B
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a H3K36-specific histone demethylase, which contains an N-terminal jumonji C domain, a CxxC zinc finger domain, a plant homeodomain finger, an F-box, and eight leucine-rich repeats. Amongst its demonstrated functions, this protein plays roles in the suppression of premature cellular senescence, leukemia maintenance and development, maintenance of mouse embryonic stem cell pluripotency, and induced pluripotent stem cell generation. Mice homozygous for a targeted deletion of the zinc finger domain display embryonic lethality with development ceasing at approximately 7 to 8 days post coitum, demonstrating an essential role in early development. A pseudogene of this gene is found on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
  • NCBI Gene ID 30841
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Mouse Kdm2b(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Kdm2b expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Mouse Kdm2b expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Mouse Kdm2b expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Mouse Kdm2b expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Mouse Kdm2b expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Kdm2b shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Mouse Kdm2b shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Mouse Kdm2b shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Mouse Kdm2b shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Kdm2b CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Kdm2b CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Kdm2b CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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