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Vectors for Mouse Kdm5b

Gene Information

  • Offical Gene Symbol Kdm5b
  • Species Mouse (Mus musculus)
  • Offical Full Name lysine demethylase 5B
  • Other Aliases 2010009J12Rik; 2210016I17Rik; D1Ertd202e; Jarid1b; PLU-1; PUT1; Plu1; RBBP2H1A; Rb-Bp2; mKIAA4034
  • Other Desigations lysine-specific demethylase 5B; [histone H3]-trimethyl-L-lysine(4) demethylase 5B; histone demethylase JARID1B; jumonji, AT rich interactive domain 1B (Rbp2 like); jumonji/ARID domain-containing protein 1B; lysine (K)-specific demethylase 5B; putative DNA/chromatin binding motif 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Homozygous mutant mice display decreased body weight, decreased female fertility, lower uterine weight, and a delay in mammary development. Knockout of this gene has also been associated with embryonic lethality. [provided by RefSeq, Dec 2016]
  • NCBI Gene ID 75605
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Kdm5b(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Kdm5b expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Kdm5b expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Kdm5b expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Kdm5b expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Kdm5b expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Kdm5b shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Kdm5b shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Kdm5b shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Kdm5b shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Kdm5b CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Kdm5b CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Kdm5b CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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