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Vectors for Mouse Ndufa2

Gene Information

  • Offical Gene Symbol Ndufa2
  • Species Mouse (Mus musculus)
  • Offical Full Name NADH:ubiquinone oxidoreductase subunit A2
  • Other Aliases B8; C1-B8; CI-B8
  • Other Desigations NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2; NADH-ubiquinone oxidoreductase B8 subunit; complex I-B8
  • Gene Type protein-coding
  • Summary
    This gene encodes a subunit of the NADH-ubiquinone oxidoreductase (complex I) enzyme, which is a large, multimeric protein. It is the first enzyme complex in the mitochondrial electron transport chain and catalyzes the transfer of electrons from NADH to the electron acceptor ubiquinone. The proton gradient created by electron transfer drives the conversion of ADP to ATP. The human ortholog of this gene has been characterized, and its structure and redox potential is reported to be similar to that of thioredoxins. It may be involved in regulating complex I activity or assembly via assistance in redox processes. In humans, mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. A pseudogene of this gene is located on chromosome 5. [provided by RefSeq, May 2013]
  • NCBI Gene ID 17991
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Ndufa2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Ndufa2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Ndufa2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Ndufa2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Ndufa2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Ndufa2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Ndufa2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Ndufa2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Ndufa2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Ndufa2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Ndufa2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Ndufa2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Ndufa2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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