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Vectors for Mouse Pclo

Gene Information

  • Offical Gene Symbol Pclo
  • Species Mouse (Mus musculus)
  • Offical Full Name piccolo (presynaptic cytomatrix protein)
  • Other Aliases Acz; Pico
  • Other Desigations protein piccolo; aczonin; brain-derived HLMN protein; multidomain presynaptic cytomatrix protein
  • Gene Type protein-coding
  • Summary
    Enables profilin binding activity. A structural constituent of presynaptic active zone. Involved in presynapse to nucleus signaling pathway; protein localization to synapse; and synaptic vesicle clustering. Acts upstream of or within cytoskeleton organization; insulin secretion; and regulation of exocytosis. Located in postsynaptic density and presynaptic active zone cytoplasmic component. Is expressed in nervous system and sensory organ. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 3. Orthologous to human PCLO (piccolo presynaptic cytomatrix protein). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 26875
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Pclo(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Pclo expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Pclo expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Pclo expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Pclo expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Pclo expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Pclo shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Mouse Pclo shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
View Vector 
Mouse Pclo shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Pclo shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Pclo CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
View Vector 
Mouse Pclo CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Pclo CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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