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Vectors for Mouse Tcf4

Gene Information

  • Offical Gene Symbol Tcf4
  • Species Mouse (Mus musculus)
  • Offical Full Name transcription factor 4
  • Other Aliases 5730422P05Rik; ASP-I2; E2-2; E2.2; ITF-2; ITF-2b; ITF2; ME2; MITF-2A; MITF-2B; SEF-2; SEF2; SEF2-1; TFE; Tcf-4; bHLHb19
  • Other Desigations transcription factor 4; MITF-2; SL3-3 enhancer factor 2; Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2); class A helix-loop-helix transcription factor ME2; immunoglobulin transcription factor-2
  • Gene Type protein-coding
  • Summary
    Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; E-box binding activity; and TFIIB-class transcription factor binding activity. Involved in positive regulation of neuron differentiation; positive regulation of transcription by RNA polymerase II; and protein-DNA complex assembly. Acts upstream of or within several processes, including negative regulation of angiogenesis; negative regulation of macromolecule metabolic process; and regulation of vascular endothelial growth factor signaling pathway. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study Pitt-Hopkins syndrome and schizophrenia. Human ortholog(s) of this gene implicated in Fuchs\' endothelial dystrophy and Pitt-Hopkins syndrome. Orthologous to human TCF4 (transcription factor 4). [provided by Alliance of Genome Resources, Apr 2022] Annotation information: Note: Tcf4 (GeneID: 21413) and Tcf7l2 (GeneID: 21416) loci share the Tcf4 symbol/alias in common. Tcf4 is a widely used alternative name for T-cell-specific transcription factor 4 (Tcf7l2) conflicting with the official symbol for transcription factor 4 (Tcf4). [26 Jun 2008]
  • NCBI Gene ID 21413
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Tcf4(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Tcf4 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Tcf4 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Tcf4 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Tcf4 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Tcf4 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Tcf4 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Tcf4 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Tcf4 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Tcf4 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Tcf4 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Tcf4 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Tcf4 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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