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Vectors for Mouse Wwox

Gene Information

  • Offical Gene Symbol Wwox
  • Species Mouse (Mus musculus)
  • Offical Full Name WW domain-containing oxidoreductase
  • Other Aliases 5330426P09Rik; 9030416C10Rik; WOX1
  • Other Desigations WW domain-containing oxidoreductase; WW-domain oxidoreductase
  • Gene Type protein-coding
  • Summary
    Enables enzyme binding activity. Contributes to transcription coactivator activity. Involved in cellular response to transforming growth factor beta stimulus; positive regulation of extrinsic apoptotic signaling pathway; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including apoptotic signaling pathway; osteoblast differentiation; and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Located in mitochondrion and nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including central nervous system; head mesenchyme derived from neural crest; musculoskeletal system; sensory organ; and spinal ganglion. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; esophageal cancer; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human WWOX (WW domain containing oxidoreductase). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 80707
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Wwox(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Wwox expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Wwox expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Wwox expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Wwox expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Wwox expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Wwox shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Wwox shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Wwox shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Wwox shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Wwox CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Wwox CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Wwox CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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