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Vectors for Rat P4hb

Gene Information

  • Offical Gene Symbol P4hb
  • Species Rat (Rattus norvegicus)
  • Offical Full Name prolyl 4-hydroxylase subunit beta
  • Other Aliases PDI; PDIR
  • Other Desigations protein disulfide-isomerase; Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide); cellular thyroid hormone-binding protein; prolyl 4-hydroxylase, beta polypeptide
  • Gene Type protein-coding
  • Summary
    Enables enzyme binding activity and protein disulfide isomerase activity. Predicted to be involved in several processes, including positive regulation of substrate adhesion-dependent cell spreading; positive regulation of viral entry into host cell; and protein folding in endoplasmic reticulum. Predicted to act upstream of or within cellular response to interleukin-7 and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Predicted to be located in several cellular components, including cytosol; endoplasmic reticulum-Golgi intermediate compartment; and lamellipodium. Predicted to be part of endoplasmic reticulum chaperone complex and procollagen-proline 4-dioxygenase complex. Predicted to be active in endoplasmic reticulum and external side of plasma membrane. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Orthologous to human P4HB (prolyl 4-hydroxylase subunit beta). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 25506
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Rat P4hb(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat P4hb expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Rat P4hb expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Rat P4hb expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Rat P4hb expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Rat P4hb expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat P4hb shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
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Rat P4hb shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Rat P4hb shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Rat P4hb shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat P4hb CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Rat P4hb CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Rat P4hb CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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