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Vectors for Rat Pclo

Gene Information

  • Offical Gene Symbol Pclo
  • Species Rat (Rattus norvegicus)
  • Offical Full Name piccolo (presynaptic cytomatrix protein)
  • Other Aliases aczonin
  • Other Desigations protein piccolo; multidomain presynaptic cytomatrix protein Piccolo; presynaptic cytomatrix protein; protein piccolo-like
  • Gene Type protein-coding
  • Summary
    Enables calcium ion binding activity; calcium-dependent phospholipid binding activity; and transcription corepressor binding activity. Involved in several processes, including positive regulation of synaptic vesicle recycling; presynaptic active zone assembly; and regulation of endosome size. Located in several cellular components, including cytoplasmic vesicle; distal axon; and rod spherule. Is active in glutamatergic synapse; parallel fiber to Purkinje cell synapse; and presynaptic active zone cytoplasmic component. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 3. Orthologous to human PCLO (piccolo presynaptic cytomatrix protein). [provided by Alliance of Genome Resources, Apr 2022] Annotation information: Note: This gene aligns across a gap in the Rnor_6.0 reference genome assembly, and therefore, the 5\' end of this gene was annotated on NW_007905776.1 and the 3\' end was annotated on NW_007905775.1 in NCBI\'s Rattus norvegicus Annotation Release 105. [15 Jun 2015]
  • NCBI Gene ID 56768
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Rat Pclo(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Pclo expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Rat Pclo expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Rat Pclo expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Rat Pclo expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Rat Pclo expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Pclo shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Rat Pclo shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Rat Pclo shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Rat Pclo shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Pclo CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Rat Pclo CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Rat Pclo CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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