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Vectors for Rat Topors

Gene Information

  • Offical Gene Symbol Topors
  • Species Rat (Rattus norvegicus)
  • Offical Full Name TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
  • Other Aliases -
  • Other Desigations E3 ubiquitin-protein ligase Topors; topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • Gene Type protein-coding
  • Summary
    Predicted to enable several functions, including DNA topoisomerase binding activity; antigen binding activity; and ubiquitin-like protein transferase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; positive regulation of ubiquitin-protein transferase activity; and protein modification by small protein conjugation. Predicted to act upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; positive regulation of transcription, DNA-templated; and regulation of cell population proliferation. Predicted to be located in centriole; nucleoplasm; and spindle pole. Predicted to be part of gamma-tubulin complex and ubiquitin ligase complex. Predicted to be active in ciliary basal body; nuclear speck; and photoreceptor connecting cilium. Predicted to colocalize with PML body. Human ortholog(s) of this gene implicated in retinitis pigmentosa 31. Orthologous to human TOPORS (TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 362501
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Rat Topors(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Topors expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Rat Topors expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Rat Topors expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Rat Topors expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Rat Topors expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Topors shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Rat Topors shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Rat Topors shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Rat Topors shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Topors CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Rat Topors CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Rat Topors CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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