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Vectors for Rat Wwox

Gene Information

  • Offical Gene Symbol Wwox
  • Species Rat (Rattus norvegicus)
  • Offical Full Name WW domain-containing oxidoreductase
  • Other Aliases -
  • Other Desigations WW domain-containing oxidoreductase
  • Gene Type protein-coding
  • Summary
    Predicted to enable enzyme binding activity and identical protein binding activity. Predicted to contribute to transcription coactivator activity. Predicted to be involved in cellular response to transforming growth factor beta stimulus; positive regulation of transcription by RNA polymerase II; and regulation of signal transduction. Predicted to act upstream of or within several processes, including apoptotic signaling pathway; osteoblast differentiation; and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in several cellular components, including Golgi apparatus; mitochondrion; and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to colocalize with microvillus and plasma membrane. Used to study epilepsy. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; esophageal cancer; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human WWOX (WW domain containing oxidoreductase). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 292041
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Rat Wwox(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Wwox expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Rat Wwox expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Rat Wwox expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Rat Wwox expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Rat Wwox expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Wwox shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Rat Wwox shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Rat Wwox shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Rat Wwox shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Wwox CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Rat Wwox CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Rat Wwox CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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