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Vectors for Rhesus macaque SELENOP

Gene Information

  • Offical Gene Symbol SELENOP
  • Species Rhesus macaque (Macaca mulatta)
  • Offical Full Name -
  • Other Aliases SEPP1
  • Other Desigations selenoprotein P; selenoprotein P, plasma, 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a selenoprotein that is predominantly expressed in the liver and secreted into the plasma. This selenoprotein is unique in that it contains multiple selenocysteine (Sec) residues per polypeptide (12 in rhesus macaque), and accounts for most of the selenium in plasma. It has been implicated as an extracellular antioxidant, and in the transport of selenium to extra-hepatic tissues via apolipoprotein E receptor-2 (apoER2). Mice lacking this gene exhibit neurological dysfunction, suggesting its importance in normal brain function. Sec is encoded by the UGA codon, which normally signals translation termination. The 3\' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The mRNA for this selenoprotein contains two SECIS elements. The use of alternative polyadenylation sites, one located in between the two SECIS elements, results in two populations of mRNAs containing either both (predominant) or just the upstream SECIS element (PMID:27881738). [provided by RefSeq, Oct 2018]
  • NCBI Gene ID 698917
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Rhesus macaque SELENOP(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rhesus macaque SELENOP expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Rhesus macaque SELENOP expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Rhesus macaque SELENOP expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Rhesus macaque SELENOP expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Rhesus macaque SELENOP expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189

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