Click to refer colleagues and get 30% off
  1. Home
  2. Find Popular Vectors
  3. Vectors for African clawed frog dio3.L

Vectors for African clawed frog dio3.L

Gene Information

  • Offical Gene Symbol dio3.L
  • Species African clawed frog (Xenopus laevis)
  • Offical Full Name deiodinase, iodothyronine, type 3 L homeolog
  • Other Aliases 5DIII; D3; DI-3; DIOIII; XL-15; dio3; itdi3; txdi3
  • Other Desigations thyroxine 5-deiodinase L homeolog; Type 3 DI; Type III iodothyronine deiodinase; Type-III 5'-deiodinase; deiodinase, iodothyronine, type III; gene 15; iodothyronine 5-deiodinase type III; type 3 deiodinase
  • Gene Type protein-coding
  • Summary
    The protein encoded by this intronless gene belongs to the iodothyronine deiodinase family. It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3\',5-triiodothyronine (T3) to inactive metabolites, 3,3\',5\'-triiodothyronine (RT3) and 3,3\'-diiodothyronine (T2), respectively. As in other verterbrates, studies in xenopus show that this enzyme is involved in early embryonic development. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3\' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. A homeolog of this gene is found on chromosome 8S. [provided by RefSeq, Jul 2017]
  • NCBI Gene ID 397779
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for African clawed frog dio3.L(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
African clawed frog dio3.L expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
African clawed frog dio3.L expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
African clawed frog dio3.L expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
African clawed frog dio3.L expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
African clawed frog dio3.L expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189

Can’t find desired vectors above? Use options below to obtain custom vectors.

Design My Vector

Use this option to design your vector using our online platform.

You can request cloning & virus packaging services for your vector here.

Request Design Support

Use this option to ask our scientists to design your vector for free.

You can also submit other service inquires here, including:

  • Virus packaging
  • CRISPR targeting
  • BAC modification
  • Library construction
  • Plasmid DNA Preparation
  • RNA preparation
  • Mutagenesis
  • and more...