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Vectors for African clawed frog gpx1.S

Gene Information

  • Offical Gene Symbol gpx1.S
  • Species African clawed frog (Xenopus laevis)
  • Offical Full Name glutathione peroxidase 1 S homeolog
  • Other Aliases gpx1; gshpx1
  • Other Desigations glutathione peroxidase 1 S homeolog
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3\' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. A homeolog of this gene is found on chromosome 4L. [provided by RefSeq, Jul 2017]
  • NCBI Gene ID 496242
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for African clawed frog gpx1.S(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
African clawed frog gpx1.S expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
African clawed frog gpx1.S expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
African clawed frog gpx1.S expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
African clawed frog gpx1.S expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
African clawed frog gpx1.S expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189

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