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Vectors for Cow GPX6

Gene Information

  • Offical Gene Symbol GPX6
  • Species Cow (Bos taurus)
  • Offical Full Name -
  • Other Aliases -
  • Other Desigations glutathione peroxidase 6; glutathione peroxidase 6 (olfactory)
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. Expression of this gene has been observed in embryos and olfactory epithelium; however, the exact function of this gene is not known. This isozyme, as in human, is a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3\' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The orthologs of this gene in mouse and rat (and some other species) contain a cysteine (Cys) residue in place of the Sec residue, and their corresponding mRNAs lack SECIS element. [provided by RefSeq, Jul 2017] Annotation information: Note: The current Bos taurus genome assembly (ARS-UCD1.2) has two copies of GPX6 gene: on chromosomes 1 (GeneID:519280) and 23 (GeneID:112443788). The location on chromosome 1 is syntenic with that of human GPX6 gene, therefore, the curated RefSeq (NM_001163142.1:NP_001156614.1), supported by homologous transcripts/EST and protein data, is associated with GeneID:519280, even though its alignment to chromosome 1 is not ideal. [20 Jun 2018]
  • NCBI Gene ID 519280
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI UCSC Genome Browser View

Popular Vector Designs for Cow GPX6(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Cow GPX6 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Cow GPX6 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Cow GPX6 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Cow GPX6 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Cow GPX6 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189

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