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Vectors for Human CEMIP2

Gene Information

  • Offical Gene Symbol CEMIP2
  • Species Human (Homo sapiens)
  • Offical Full Name cell migration inducing hyaluronidase 2
  • Other Aliases TMEM2
  • Other Desigations inactive cell surface hyaluronidase CEMIP2; cell surface hyaluronidase; transmembrane protein 2
  • Gene Type protein-coding
  • Summary
    This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]
  • NCBI Gene ID 23670
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CEMIP2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CEMIP2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human CEMIP2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human CEMIP2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human CEMIP2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human CEMIP2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CEMIP2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human CEMIP2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human CEMIP2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human CEMIP2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CEMIP2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human CEMIP2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human CEMIP2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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