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Vectors for Human LRRC8A

Gene Information

  • Offical Gene Symbol LRRC8A
  • Species Human (Homo sapiens)
  • Offical Full Name leucine rich repeat containing 8 VRAC subunit A
  • Other Aliases AGM5; HsLRRC8A; LRRC8; SWELL1
  • Other Desigations volume-regulated anion channel subunit LRRC8A; leucine rich repeat containing 8 family member A; leucine-rich repeat-containing protein 8A; swelling protein 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 56262
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human LRRC8A(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LRRC8A expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human LRRC8A expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human LRRC8A expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human LRRC8A expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human LRRC8A expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LRRC8A shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human LRRC8A shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human LRRC8A shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human LRRC8A shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LRRC8A CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human LRRC8A CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human LRRC8A CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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