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Vectors for Human SPTBN2

Gene Information

  • Offical Gene Symbol SPTBN2
  • Species Human (Homo sapiens)
  • Offical Full Name spectrin beta, non-erythrocytic 2
  • Other Aliases GTRAP41; SCA5; SCAR14
  • Other Desigations spectrin beta chain, non-erythrocytic 2; beta-III spectrin; glutamate transporter EAAT4-associated protein 41; spectrin beta III sigma 2; spectrin beta chain, brain 2; spectrin, non-erythroid beta chain 2; spinocerebellar ataxia 5 protein
  • Gene Type protein-coding
  • Summary
    Spectrins are principle components of a cell\'s membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
  • NCBI Gene ID 6712
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human SPTBN2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPTBN2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human SPTBN2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human SPTBN2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human SPTBN2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human SPTBN2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPTBN2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human SPTBN2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human SPTBN2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human SPTBN2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPTBN2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human SPTBN2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human SPTBN2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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