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Vectors for Mouse App

Gene Information

  • Offical Gene Symbol App
  • Species Mouse (Mus musculus)
  • Offical Full Name amyloid beta precursor protein
  • Other Aliases Abeta; Abpp; Adap; Ag; Cvap; E030013M08Rik; betaApp
  • Other Desigations amyloid-beta precursor protein; alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid precursor protein; amyloidogenic glycoprotein; appican; beta-amyloid precursor protein; protease nexin II
  • Gene Type protein-coding
  • Summary
    Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; low-density lipoprotein particle receptor binding activity; and signaling receptor activator activity. Involved in negative regulation of blood circulation; positive regulation of endothelin production; and positive regulation of tumor necrosis factor production. Acts upstream of or within several processes, including cellular metal ion homeostasis; nervous system development; and regulation of cellular protein metabolic process. Located in several cellular components, including cytoplasmic vesicle; cytoskeleton; and neuromuscular junction. Is integral component of membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; neurogenic placode; and sensory organ. Used to study Alzheimer\'s disease. Human ortholog(s) of this gene implicated in APP-related cerebral amyloid angiopathy; Alzheimer\'s disease; Alzheimer\'s disease 1; cognitive disorder; and visual epilepsy. Orthologous to human APP (amyloid beta precursor protein). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 11820
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse App(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse App expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse App expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse App expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse App expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse App expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse App shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse App shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse App shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse App shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse App CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse App CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse App CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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