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Vectors for Mouse Arhgef2

Gene Information

  • Offical Gene Symbol Arhgef2
  • Species Mouse (Mus musculus)
  • Offical Full Name Rho/Rac guanine nucleotide exchange factor 2
  • Other Aliases GEF; GEF-H1; GEFH1; LFP40; Lbcl1; Lfc; P40; mKIAA0651
  • Other Desigations rho guanine nucleotide exchange factor 2; LBC'S first cousin; guanine nucleotide exchange factor H1; lymphoid blast crisis-like 1; oncogene LFC; rho/rac guanine nucleotide exchange factor (GEF) 2; rhobin
  • Gene Type protein-coding
  • Summary
    Enables guanyl-nucleotide exchange factor activity and microtubule binding activity. Involved in several processes, including establishment of mitotic spindle orientation; generation of neurons; and positive regulation of neuron migration. Acts upstream of or within several processes, including actin filament organization; negative regulation of podosome assembly; and regulation of Rho protein signal transduction. Located in several cellular components, including dendritic shaft; podosome; and postsynaptic density. Is expressed in several structures, including brain; dorsal root ganglion; and testis. Used to study neurodevelopmental disorder with midbrain and hindbrain malformations. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with midbrain and hindbrain malformations. Orthologous to human ARHGEF2 (Rho/Rac guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 16800
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Arhgef2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Arhgef2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Arhgef2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Arhgef2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Arhgef2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Arhgef2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Arhgef2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Arhgef2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Arhgef2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Arhgef2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Arhgef2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Arhgef2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Arhgef2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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