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Vectors for Mouse Klrk1

Gene Information

  • Offical Gene Symbol Klrk1
  • Species Mouse (Mus musculus)
  • Offical Full Name killer cell lectin-like receptor subfamily K, member 1
  • Other Aliases D6H12S2489E; NKG2-D; Nkg2d
  • Other Desigations NKG2-D type II integral membrane protein; NK cell receptor D; NKG2-D-activating NK receptor; natural killer cell group 2D
  • Gene Type protein-coding
  • Summary
    Enables several functions, including MHC class I protein binding activity; MHC class Ib receptor activity; and identical protein binding activity. Involved in positive regulation of natural killer cell mediated cytotoxicity. Acts upstream of or within several processes, including positive regulation of interferon-gamma production; positive regulation of nitric oxide biosynthetic process; and response to bacterium. Located in external side of plasma membrane. Human ortholog(s) of this gene implicated in tropical spastic paraparesis. Orthologous to several human genes including KLRC4-KLRK1 (KLRC4-KLRK1 readthrough). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 27007
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Klrk1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Klrk1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Klrk1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Klrk1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Klrk1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Klrk1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Klrk1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Klrk1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Klrk1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Klrk1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Klrk1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Klrk1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Klrk1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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